Liposomal Glutathione

by Tim Guilford, MD

Recent advances in liposome technology now allow glutathione to be provided in a stable, oral dietary supplement. Basic science research shows that glutathione works as both an antioxidant and a detoxifying agent. Glutathione plays a very fundamental role in protecting against oxidative stress. Glutathione’s advantage over vitamins C and E is that it works with enzymes that increase its utility.

A study using liposomal glutathione showed for the first time that the enzyme glutathione peroxidase is found to be naturally embedded in LDL cholesterol. Liposomal glutathione was able to slow the oxidation of LDL cholesterol and to slow the formation of the vascular plaque in the animal model. Glutathione-S transferase (GST) is an enzyme linking glutathione to toxins. When it is low, there can be an increased risk for a number of conditions associated with low glutathione. The findings of the animal study suggest that liposomal glutathione may be useful in supporting normal glutathione levels and function.

Glutathione has been found to be low in the bronchiolar lining fluid of the lung during bronchospasm and to be low in the brain cells that produce the dopamine involved in facilitating movement in neurodegenerative conditions. The role that glutathione plays as an antioxidant and detoxifying agent and its role in supporting normal immune function will be reviewed in the presentation.

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