Dear Dr. Dean:Last year I was taking your Oral ChelatoRx and this year I started taking IV chelation. There was a major change at first.Now I dont notice any change but still have angina pains from time to time. This seems to happen more on the day of chelation. At this point I have cut back on half my blood pressure meds. & a third of my diabetes meds. Yesterday was my 26th treatment & at this point I have them once per week. Three questions I have are as follows: 1st at what point should you give up on IV chelation & see a cardiologist? 2nd would it be beneficial to again start with the Oral as well as the IV Chelation? 3rd should you not monitor kidney function with oral chelation?SP
Dear SP To respond in order:First I would never give up on chelation either oral or IV. There may be times when other modalities may be necessary but none of these other modalities do what chelation does—i.e. improve the microcirculation where the oxygen and nutrient exchange actually takes place. Second I would definitely continue with Oral Chelation in addition to IV chelation. I now recommend that my IV chelation patients continue with oral chelation as well. The presence of the low blood levels of EDTA that are maintained with oral chelation has continuing benefits in terms of elimination of heavy metals and prevention of thromboses. On the other hand the stimulation of parathyroid hormone to enhance calcium metabolism occurs only with IV chelation with the fairly large but short-lived bolus of EDTA (it is completely excreted within 24 hours).Third it is not necessary to monitor kidney function with oral EDTA. Oral EDTA is poorly absorbed by the GI tract. Only about 5-15% is absorbed. Consequently of a one gram dose (amount in ten Oral ChelatoRx capsules) only 50-150 mg is absorbed. Over a month thats 1 500-4 500 mg absorbed. Most physicians administer EDTA intravenously in doses of 1 500-3 000 mg at a time. Therefore a months worth of Oral ChelatoRx is equivalent to about one intravenous chelation. Therefore there is negligible risk of kidney toxicity with oral EDTA chelation.Considering your continuing symptoms I would suggest adding Turmeric Extract Co Q10 and extra niacin (work up to 1 500-3 000 mg) to your daily regimen. Also AGE-Block as a means to maintain stable glucose and insulin levels.Hope this answers your questions. Ward Dean M.D.