5-HTP/DHEA

Dear Dr. Meletis, I take lisinopril for high blood pressure and citalopram for depression. Would taking 5-HTP and DHEA cause any problems? Ms. R.

Dear Ms. R., Depending on your age and overall health, both 5-HTP and DHEA are commonly used as part of a healthy aging protocol. DHEA in a small dose would be the best way to start, unless you have measured your DHEA levels with a Salivary Hormone Test. This test is available here, or your physician may have already ordered one for you. There is a small group of people that can experience an increase in blood pressure with DHEA, so monitoring your blood pressure to see how your body is responding would be important. Since you are thinking about adding 5-HTP, may I assume that the current anti-depressant is not fully working? If that is the case, 5-HTP may be a very reasonable consideration, yet once again starting with a small dose in the evening and over the course of several weeks, seeing how well you tolerate it, would be an important consideration. There is also a test available here, called an Organic Acid Test, that could help you better identify which nutrient your body specifically may need. It measures how well your body uniquely processes protein, fats and carbohydrates, and also brain chemistry and cellular energy. The concern with adding 5-HTP to your current routine is that it can have an additive effect to your current anti-depressant. Some general consideration that my patients employ relative to blood pressure and depression include getting 8 hours of sleep per night, and make sure you do not snore. If you do snore, and don’t wake up rested or stop breathing at night, getting evaluated for sleep apnea is a must. Sleep apnea can cause both high blood pressure and depression. Drinking 64 ounces of water per day is a must as well, and some mild age and fitness appropriate exercise can also significantly help with both blood pressure and depression. Lastly, you may wish to look at Pressure-FX®, DHA (fish oil) and Magnesium relative to your wellness program. The following information is educational and is not intended as either treatment or diagnosis. Working closely with your personal health care provider is essential. Sincerely, Chris D. Meletis, ND