Review Finds Key Nutrients Reduce Risk of Age-Related Macular Degeneration
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By VRP Staff
A review from the Division of Epidemiology and Clinical Research, National Eye Institute and the National Institutes of Health (NIH) has found that vitamins C, E, beta-carotene and zinc reduce the risk of advanced age-related macular degeneration (AMD) and that supplements containing these nutrients are appropriate for individuals with intermediate AMD or advanced AMD in one eye. Furthermore, the review also found that lutein, zeaxanthin and omega-3 fatty acids also play a role in reducing the risk of AMD.
The review assessed the role that certain nutrients play in age-related macular degeneration, a leading cause of vision loss in persons with European ancestry. The reviewers evaluated both observational and interventional studies to determine whether nutrition is associated with age-related macular degeneration.
In addition to reporting on the effects of vitamin C, E, beta carotene and zinc, the review also found that results of observational data suggest that high dietary intake of lutein and zeaxanthin are associated with a lower risk of advanced age-related macular degeneration. Similarly, omega-3 fatty acids derived from fish consumption are also associated with a decreased risk of advanced age-related macular degeneration.
The scientists concluded those with AMD or advanced AMD (neovascular or central geographic atrophy) in one eye should consider taking beta-carotene, zinc, and vitamins C and E. Furthermore, evaluation of lutein, zeaxanthin and omega-3 fatty acids will be conducted in the controlled, randomized trial known as the Age-Related Eye Disease Study 2 (AREDS2).
Reference:
Coleman H, Chew E. Nutritional Supplementation in Age-Related Macular Degeneration, Retinal, Vitreous and Macular Disorders. Current Opinion in Ophthalmology. May 2007;18(3):220-223.

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